Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PLG | P00747 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | PLAT | P00750 | 3/20 | 0.39 |
| ▸ | KLK8 | O60259 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27836744 | 0.74 | TSHR (0.43) | TSHRFOLH1CETPALDH1A1KDM4E | |
| SCHEMBL11303293 | 0.72 | TSHR (0.55) | TSHRFOLH1CETPALDH1A1KDM4E | |
| SCHEMBL31549517 | 0.71 | TSHR (0.53) | TSHRFOLH1CETPALDH1A1KDM4E | |
| SCHEMBL29739976 | 0.71 | LAP3 (0.35) | — | |
| SCHEMBL10832549 | 0.69 | TSHR (0.58) | TSHRFOLH1CETPALDH1A1KDM4E | |
| SCHEMBL10832425 | 0.68 | TSHR (0.62) | TSHRFOLH1CETPALDH1A1KDM4E | |
| SCHEMBL13711507 | 0.68 | TSHR (0.57) | TSHRFOLH1CETPALDH1A1KDM4E | |
| SCHEMBL27474327 | 0.68 | NOS3 (0.36) | — | |
| SCHEMBL7376210 | 0.68 | TSHR (0.53) | TSHRFOLH1CETPSLC1A3SLC1A2 | |
| SCHEMBL7376215 | 0.68 | TSHR (0.53) | TSHRFOLH1CETPSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102153587-B | Method for synthesizing dibenzyloxy-phosphoryl creatinine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-102153587-A | Method for synthesizing dibenzyloxy-phosphoryl creatinine | NANJING EAST SUNSCREEN PHARMACEUTICAL CO LTD | 2011-08-17 | — | — | CN | disclosed |