Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000380 | 0.77 | ALDH1A1 (0.59) | MYCKDM4ECDK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27837258 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1TDP1 | |
| SCHEMBL2500845 | 0.74 | MYC (0.61) | MYCKDM4EMPOCDK1SMN1; SMN2 | |
| SCHEMBL1671246 | 0.73 | MYC (0.56) | MYCKDM4ECDK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL1655468 | 0.73 | MYC (0.56) | MYCKDM4EMPOCDK1SMN1; SMN2 | |
| SCHEMBL30777877 | 0.73 | MYC (0.56) | MYCKDM4ECDK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10334083 | 0.73 | CFD (0.63) | MYCKDM4ECDK1SMN1; SMN2ALDH1A1 | |
| Water SCHEMBL27924364 | 0.72 | MYC (0.55) | MYCKDM4ECDK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL24381725 | 0.72 | MYC (0.55) | MYCKDM4ECDK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL170522 | 0.72 | KDM4C (0.62) | MYCKDM4ESMN1; SMN2ALDH1A1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164911-A | 1H-benzimidazole-5-carboxamides as anti-inflammatory agents | BOEHRINGER INGELHEIM INT | 2011-08-24 | — | — | CN | disclosed |