Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29451094 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL6664968 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL22834182 | 0.80 | MEN1 (0.58) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL29451098 | 0.80 | MEN1 (0.58) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL25584212 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL27799802 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL27837204 | 0.76 | MYC (0.48) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL98371 | 0.74 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL2651040 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL653785 | 0.72 | GAA (0.56) | ALDH1A1KDM4EHPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164911-A | 1H-benzimidazole-5-carboxamides as anti-inflammatory agents | BOEHRINGER INGELHEIM INT | 2011-08-24 | — | — | CN | disclosed |