Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664968 | 1.00 | ALDH1A1 (0.55) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL22834182 | 0.98 | MEN1 (0.58) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL29451098 | 0.98 | MEN1 (0.58) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29451106 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL696299 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL18160484 | 0.83 | PTGS1 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL27837258 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL25584212 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8924033 | 0.80 | RXRA (0.50) | ALDH1A1KDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL653785 | 0.79 | GAA (0.56) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823106-A | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114144520-B | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2022169891-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THE SAME | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-08-11 | — | — | WO | disclosed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |