Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857285 | 0.93 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HPGDKDM4EKCNJ1 | |
| SCHEMBL31696865 | 0.87 | CTSB (0.54) | ALDH1A1SMN1; SMN2KDM4EKCNJ1LMNA | |
| SCHEMBL27837694 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HPGDKCNJ1KCNH2 | |
| SCHEMBL32662599 | 0.82 | CYP1A2 (0.46) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL31696858 | 0.81 | CTSB (0.52) | ALDH1A1SMN1; SMN2KDM4EKCNJ1LMNA | |
| SCHEMBL20299855 | 0.80 | BCL9 (0.44) | ALDH1A1SMN1; SMN2HPGDLMNAGAA | |
| SCHEMBL27573003 | 0.79 | TSHR (0.46) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL28102381 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDLMNAGAA | |
| SCHEMBL11613240 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDLMNA | |
| SCHEMBL5742091 | 0.78 | KMT2A (0.45) | ALDH1A1SMN1; SMN2HPGDLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026976-A | Morpholine derivatives as anti-obesity agents | BIOVITRUM AB PUBL | 2011-04-20 | — | — | CN | disclosed |