Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27837565 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTKCNJ1KCNH2 | |
| SCHEMBL26122711 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTKCNJ1KCNH2 | |
| SCHEMBL31696865 | 0.80 | CTSB (0.54) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL4573720 | 0.80 | KCNJ1 (0.65) | ALDH1A1LMNAMAPTKCNJ1KCNH2 | |
| SCHEMBL5857285 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTKCNJ1SMN1; SMN2 | |
| SCHEMBL402901 | 0.79 | SIGMAR1 (0.58) | ALDH1A1LMNAMAPTKCNJ1KCNH2 | |
| SCHEMBL30105726 | 0.77 | CTSB (0.59) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7011905 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL22117865 | 0.77 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTKCNH2SMN1; SMN2 | |
| SCHEMBL18910916 | 0.77 | MAPT (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026976-A | Morpholine derivatives as anti-obesity agents | BIOVITRUM AB PUBL | 2011-04-20 | — | — | CN | disclosed |