Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 6/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535701 | 0.84 | MAOA (0.54) | MAOAMAOBARPDK2SLC18A3 | |
| SCHEMBL8284787 | 0.84 | MAOA (0.54) | MAOAMAOBARPDK2SLC18A3 | |
| Methyl Alcohol SCHEMBL27841069 | 0.81 | SLC18A3 (0.53) | MAOAMAOBARPDK2SLC18A3 | |
| SCHEMBL6446083 | 0.81 | MMP2 (0.41) | GRM5APPMMP2MMP9 | |
| SCHEMBL13651291 | 0.80 | ALDH1A1 (0.51) | AR | |
| SCHEMBL18787366 | 0.80 | ALDH1A1 (0.51) | AR | |
| SCHEMBL7075696 | 0.79 | MAOA (0.60) | MAOAMAOBARPDK2SLC18A3 | |
| SCHEMBL24824101 | 0.75 | HRH3 (0.49) | MAOAMAOBARPDK2ACHE | |
| SCHEMBL18786266 | 0.75 | HRH3 (0.49) | MAOAMAOBARPDK2ACHE | |
| SCHEMBL251319 | 0.75 | ALDH1A1 (0.50) | MAOAMAOBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608369-A2 | USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION | CHIRON CORPORATION (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004087153-A2 | USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION | CHIRON CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |