SCHEMBL27844762

SCHEMBL27844762

C=C(C)c1ccccc1C(C)N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
NFKB1 P19838 1/20 0.39
PNMT P11086 1/20 0.39
LMNA P02545 3/20 0.38
ALDH1A1 P00352 2/20 0.38
GLA P06280 1/20 0.38
ADRA2A P08913 2/20 0.38
ADRA2C P18825 2/20 0.38
ADRA2B P18089 1/20 0.38
HIF1A Q16665 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
TSHR P16473 2/20 0.32
FAAH O00519 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1362730 0.85 GABRA1 (0.50) CYP1A2CYP3A4LMNAADRA2AADRA2C
Hydrogen Peroxide SCHEMBL9619640 0.83 GABRA1 (0.48) CYP1A2CYP3A4LMNAADRA2AADRA2C
SCHEMBL7550549 0.81 GABRA1 (0.37) CYP1A2CYP3A4LMNAADRA2AADRA2C
SCHEMBL10726252 0.79 IRAK4 (0.43) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL28814411 0.79 IRAK4 (0.43) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL20077832 0.79 ADRA2A (0.30) ADRA2AADRA2CADRA2B
SCHEMBL487601 0.78 HPGD (0.35) CYP1A2CYP3A4LMNAADRA2AADRA2C
SCHEMBL9064199 0.76 TYR (0.44) LMNAALDH1A1ADRA2AADRA2CHIF1A
SCHEMBL731619 0.75 IRAK4 (0.52) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL1449566 0.75 ALDH1A1 (0.52) LMNAALDH1A1ADRA2AADRA2CHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed
CN-102382257-B Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO 2015-02-11 CN disclosed
CN-104334629-A Tread rubber composition and pneumatic tire SUMITOMO RUBBER IND 2015-02-04 CN disclosed
CN-102432759-A Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL CO 2012-05-02 CN disclosed
CN-102382257-A Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO 2012-03-21 CN disclosed
CN-102382258-A Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO 2012-03-21 CN disclosed
CN-102286130-A Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer 2011-12-21 CN disclosed