Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 6/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862533 | 0.93 | FAAH (0.46) | BRAFMAPTLMNAALDH1A1GAA | |
| SCHEMBL28793758 | 0.89 | BRAF (0.45) | SRCBRAFMAPTLMNAALDH1A1 | |
| SCHEMBL27862281 | 0.89 | BRAF (0.45) | BRAFMAPTLMNAALDH1A1GAA | |
| SCHEMBL27844944 | 0.88 | ABL1 (0.50) | SRCBRAFMAPTLMNAALDH1A1 | |
| SCHEMBL27844969 | 0.87 | BRAF (0.45) | BRAFMAPTLMNAALDH1A1GAA | |
| SCHEMBL27844948 | 0.87 | BRAF (0.44) | BRAFMAPTLMNAALDH1A1GAA | |
| SCHEMBL28796270 | 0.87 | BRAF (0.46) | BRAFKDRMAPK14CCNCCDK8 | |
| SCHEMBL14146761 | 0.86 | BRAF (0.58) | BRAFKDRMAPK14 | |
| SCHEMBL27844960 | 0.86 | CCR2 (0.46) | BRAFMAPTLMNAALDH1A1GAA | |
| SCHEMBL27844954 | 0.86 | BRAF (0.54) | SRCBRAFBLMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250065-A | Substituted triazine phenyl urea derivatives and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2011-11-23 | — | — | CN | disclosed |