Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 3/20 | 0.40 |
| ▸ | KIT | P10721 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862533 | 0.90 | FAAH (0.46) | BRAFLMNAMAPTALDH1A1GAA | |
| SCHEMBL27844968 | 0.89 | SRC (0.45) | BRAFLMNAMAPTALDH1A1GAA | |
| SCHEMBL27844948 | 0.88 | BRAF (0.44) | BRAFLMNAMAPTALDH1A1GAA | |
| SCHEMBL27862281 | 0.87 | BRAF (0.45) | BRAFLMNAMAPTALDH1A1GAA | |
| SCHEMBL27862199 | 0.86 | BRAF (0.51) | BRAFLMNAMAPTALDH1A1GAA | |
| SCHEMBL14146761 | 0.86 | BRAF (0.58) | BRAFCA9KDRMAPK14 | |
| SCHEMBL27844969 | 0.85 | BRAF (0.45) | BRAFLMNAMAPTALDH1A1GAA | |
| SCHEMBL28796270 | 0.85 | BRAF (0.46) | BRAFCA9KDRTRPV1MAPK14 | |
| SCHEMBL27844960 | 0.84 | CCR2 (0.46) | BRAFLMNAMAPTALDH1A1GAA | |
| SCHEMBL27845100 | 0.84 | BRAF (0.43) | BRAFLMNAMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250065-A | Substituted triazine phenyl urea derivatives and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2011-11-23 | — | — | CN | disclosed |