Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256764 | 0.86 | ALDH1A1 (0.41) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL30484154 | 0.83 | KDM4E (0.60) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL27846553 | 0.80 | PDK2 (0.49) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL19847517 | 0.80 | KDM4E (0.47) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL19847527 | 0.76 | KDM4E (0.43) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL19847544 | 0.75 | ALDH1A1 (0.44) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL20581822 | 0.73 | KDM4E (0.56) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL9246341 | 0.72 | HSD17B10 (0.63) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL2616077 | 0.72 | KMT2A (0.46) | KDM4EMEN1LMNAMAPTOPRK1 | |
| Benzidine SCHEMBL28857193 | 0.71 | KDM4E (0.53) | KDM4EMEN1LMNAMAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102391130-A | Preparation method of 9, 9- diamino-(4-aminophenyl) fluorene | SHANGHAI GUCHUANG CHEMICAL NEW MATERIALS CO LTD | 2012-03-28 | — | — | CN | disclosed |