SCHEMBL4256764

SCHEMBL4256764

NC1(N)c2ccccc2-c2cccc(-c3ccccc3)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
THRB P10828 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
DPP4 P27487 1/20 0.38
HPGD P15428 1/20 0.37
BCL2L1 Q07817 1/20 0.37
CYP2A6 P11509 1/20 0.37
MAPK1 P28482 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
BCAT2 O15382 1/20 0.35
PDK2 Q15119 4/20 0.35
MAP4K4 O95819 1/20 0.34
CSF1R P07333 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27846342 0.86 KDM4E (0.48) ALDH1A1HSD17B10TDP1MEN1KMT2A
SCHEMBL8984765 0.80 ALDH1A1 (0.39) ALDH1A1HSD17B10THRBTDP1DPP4
SCHEMBL25818400 0.78 THRB (0.43) ALDH1A1HSD17B10THRBTDP1DPP4
SCHEMBL2616077 0.77 KMT2A (0.46) ALDH1A1THRBTDP1MEN1KMT2A
SCHEMBL7045215 0.75 PDK2 (0.43) TDP1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL28437143 0.75 PDK2 (0.42) ALDH1A1HSD17B10THRBTDP1DPP4
SCHEMBL29919652 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10THRBTDP1HPGD
SCHEMBL30084636 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10THRBTDP1HPGD
SCHEMBL706442 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10THRBTDP1HPGD
SCHEMBL30741411 0.75 THRB (0.50) ALDH1A1HSD17B10THRBTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101515632-A Organic light-emitting element YAMAGATA PROMOTIONAL ORG IND (JP) 2009-08-26 CN disclosed
US-20090206742-A1 ORGANIC LIGHT-EMITTING ELEMENT YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY 2009-08-20 US disclosed
EP-2091094-A2 Organic light-emitting element Yamagata Promotional Organization for Industrial Technology (JP) 2009-08-19 EP disclosed