Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437143 | 0.84 | PDK2 (0.42) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL25818400 | 0.84 | THRB (0.43) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL27846342 | 0.83 | KDM4E (0.48) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL27846553 | 0.81 | PDK2 (0.49) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL20581822 | 0.81 | KDM4E (0.56) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL19847517 | 0.81 | KDM4E (0.47) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL30484149 | 0.81 | PDK2 (0.44) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL19299598 | 0.81 | PDK2 (0.45) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL26808414 | 0.81 | ALDH1A1 (0.41) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL19283454 | 0.81 | PDK2 (0.44) | KDM4EMEN1LMNAMAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225733-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2023-08-16 | — | — | EP | disclosed |