Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651143 | 0.84 | PKM (0.50) | KDM4EHSD17B10 | |
| SCHEMBL7810834 | 0.74 | KIF11 (0.42) | KDM4E | |
| Bromide SCHEMBL116435 | 0.73 | TLR8 (0.46) | TGFBR1NR3C1PGRGRIN1GRIN2B | |
| SCHEMBL3433378 | 0.71 | TGFBR1 (0.51) | TGFBR1NR3C1PGRGRIN1GRIN2B | |
| SCHEMBL1263144 | 0.71 | TSHR (0.58) | PGRMAOBKDM1A | |
| SCHEMBL29678302 | 0.71 | TSHR (0.58) | PGRMAOBKDM1A | |
| SCHEMBL3474070 | 0.69 | TGFBR1 (0.49) | TGFBR1NR3C1PGRGRIN1GRIN2B | |
| SCHEMBL7815089 | 0.69 | HTR1D (0.36) | PGRHSD17B10 | |
| SCHEMBL26827704 | 0.69 | MAOB (0.62) | PGRMAOBKDM1A | |
| Ammonia Solution, Strong SCHEMBL20472961 | 0.69 | MAOB (0.56) | PGRMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414210-A | Substituted imidazo [1,2-a ] pyridine derivatives as beta-secretase inhibitors, pharmaceutical compositions, and methods of use | HIGH POINT PHARMACEUTICALS LLC | 2012-04-11 | — | — | CN | disclosed |