Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718646 | 0.79 | IDO1 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7076978 | 0.77 | LMNA (0.44) | ALDH1A1MAPTSTING1KDM4EHSD17B10 | |
| SCHEMBL8980842 | 0.75 | ALDH1A1 (0.37) | MGLLALDH1A1MAPTTSHRGRM5 | |
| SCHEMBL8772892 | 0.73 | GRM5 (0.48) | TSHRGRM5 | |
| SCHEMBL10509165 | 0.72 | CYP1A2 (0.41) | MGLLALDH1A1MAPTGRM5KDM4E | |
| SCHEMBL27487817 | 0.72 | PTGS1 (0.50) | PTGS1PTGS2MGLLTUBB4ATUBB | |
| SCHEMBL28226645 | 0.70 | KDM4E (0.50) | MGLLTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5859161 | 0.69 | GAA (0.52) | PTGS1PTGS2MGLLALDH1A1MAPT | |
| SCHEMBL29946847 | 0.69 | GAA (0.52) | PTGS1PTGS2MGLLALDH1A1MAPT | |
| SCHEMBL30239650 | 0.69 | GRM4 (0.45) | MGLLGRM5USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549054-B | Vonoprazan fumarate intermediate and preparation method thereof | 鲁南制药集团股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117247344-A | Preparation method of voronoi intermediate 5- (2-fluorophenyl) -1H-pyrrole-3-carbonitrile | 安徽迪合永欣药业有限公司 | 2023-12-19 | — | — | CN | claimed |
| WO-2025098443-A1 | METHOD FOR PREPARING 1-[5-(2-FLUOROPHENYL)-1-{[3-(3-METHOXYPROPOXY)PHENYL]SULFONYL}-1H-PYRROL-3-YL]-N-METHYLMETHYLAMINE AND HYDROCHLORIDE THEREOF | 江苏柯菲平医药股份有限公司 | 2025-05-15 | — | — | WO | disclosed |
| CN-118344276-A | Preparation method of voronoi fumarate intermediate | 北京艾湃克斯医药研发有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113511995-B | Preparation method of 5- (2-fluorophenyl) -1H-pyrrole-3-formaldehyde | 四川科伦药物研究院有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117924141-A | Preparation method of voronoi fumarate key impurities A and B | 北京北陆益康医药研发有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113549054-B | Vonoprazan fumarate intermediate and preparation method thereof | 鲁南制药集团股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117126093-B | Preparation method of voronoi intermediate | 潍坊医学院 | 2023-12-29 | — | — | CN | disclosed |
| CN-117247344-A | Preparation method of voronoi intermediate 5- (2-fluorophenyl) -1H-pyrrole-3-carbonitrile | 安徽迪合永欣药业有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117247344-A | Preparation method of voronoi intermediate 5- (2-fluorophenyl) -1H-pyrrole-3-carbonitrile | 安徽迪合永欣药业有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117247344-A | Preparation method of voronoi intermediate 5- (2-fluorophenyl) -1H-pyrrole-3-carbonitrile | 安徽迪合永欣药业有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117126093-A | Preparation method of voronoi intermediate | 潍坊医学院 | 2023-11-28 | — | — | CN | disclosed |
| CN-116621813-A | Preparation and purification method of voronoi fumarate | 合肥信风科技开发有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-113549054-A | Vonoprazan fumarate intermediate and preparation method thereof | 鲁南制药集团股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-110028436-B | Preparation method of Vonoprazan key intermediate | 杭州中美华东制药有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-108203450-A | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2018-06-26 | — | — | CN | disclosed |
| CN-102421753-A | Process for preparing azole compounds | TAKEDA PHARMACEUTICAL | 2012-04-18 | — | — | CN | disclosed |