Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946847 | 1.00 | GAA (0.52) | GAAKDM4ELMNAMEN1KMT2A | |
| SCHEMBL5716210 | 0.80 | ALDH1A1 (0.45) | GAAKDM4ELMNAMEN1KMT2A | |
| SCHEMBL12841362 | 0.75 | RAB9A (0.44) | KDM4ELMNAMEN1KMT2AMGLL | |
| SCHEMBL300039 | 0.75 | PTGS1 (0.40) | GAAKDM4ELMNAMEN1KMT2A | |
| SCHEMBL29793891 | 0.73 | IDO1 (0.61) | GAALMNAMEN1KMT2AMAPK1 | |
| SCHEMBL2587178 | 0.73 | IDO1 (0.61) | GAALMNAMEN1KMT2AMAPK1 | |
| SCHEMBL172523 | 0.73 | ALDH1A1 (0.41) | GAAKDM4ELMNAALDH1A1POLB | |
| SCHEMBL5715769 | 0.73 | CYP19A1 (0.40) | GAAKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL10075587 | 0.72 | ALDH1A1 (0.74) | GAAKDM4ELMNAMGLLALDH1A1 | |
| SCHEMBL10074488 | 0.72 | KDM4E (0.41) | GAAKDM4ELMNAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187852-B | A kind of preparation method of Vonoprazan fumarate intermediate | 江西同和药业股份有限公司 | 2019-01-15 | — | — | CN | claimed |
| CN-104418786-A | 1-(2-fluorophenyl)pyrrole and preparation method thereof | TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD | 2015-03-18 | — | — | CN | claimed |
| CN-108475731-B | Organic semiconductor material and use thereof in organic components | 赫里亚泰克有限责任公司 | 2022-07-26 | — | — | CN | disclosed |
| EP-3398214-B1 | ORGANIC SEMICONDUCTING MATERIAL AND USE THEREOF IN ORGANIC DEVICES | HELIATEK GMBH (DE) | 2022-03-16 | — | — | EP | disclosed |
| US-11063222-B2 | Organic semiconducting material and use thereof in organic devices | HELIATEK GMBH (DE) | 2021-07-13 | — | — | US | disclosed |
| CN-105524046-B | The method for preparing azole compounds | 武田药品工业株式会社 | 2019-03-29 | — | — | CN | disclosed |
| CN-106187852-B | A kind of preparation method of Vonoprazan fumarate intermediate | 江西同和药业股份有限公司 | 2019-01-15 | — | — | CN | disclosed |
| US-20190006599-A1 | ORGANIC SEMICONDUCTING MATERIAL AND USE THEREOF IN ORGANIC DEVICES | HELIATEK GMBH (DE) | 2019-01-03 | — | — | US | disclosed |
| EP-3188270-B1 | ORGANIC SEMI-CONDUCTING MATERIAL AND ITS USE IN ORGANIC COMPONENTS | HELIATEK GMBH (DE) | 2018-12-26 | — | — | EP | disclosed |
| EP-3398214-A1 | ORGANIC SEMICONDUCTING MATERIAL AND USE THEREOF IN ORGANIC DEVICES | Heliatek GmbH (DE) | 2018-11-07 | — | — | EP | disclosed |
| CN-108129374-A | The method for preparing azole compounds | 武田药品工业株式会社 | 2018-06-08 | — | — | CN | disclosed |
| CN-1889955-A | Tricyclic imidazopyridines for use as gastric secretion inhibitors | ALTANA PHARMA AG (DE) | 2007-01-03 | — | — | CN | disclosed |
| US-20060148796-A1 | 6-Substituted imidazopyrazines | ALTANA PHARMA AG (DE) | 2006-07-06 | — | — | US | disclosed |
| US-7034018-B2 | Substituted pyrrole mannich bases to combat pain and allergic reactions | GRUENENTHAL GMBH (DE) | 2006-04-25 | — | — | US | disclosed |
| CN-1247542-C | Substituted pyrrole Mannich bases to treating paint and allergic reactions | GREENTHAL GMBH (DE) | 2006-03-29 | — | — | CN | disclosed |
| EP-1246799-B1 | SUBSTITUTED PYRROLE MANNICH BASES TO COMBAT PAIN AND ALLERGIC REACTIONS | GRUENENTHAL GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| CN-1414950-A | Substituted pyrrole mannich bases for the treatment of pain and hypersensitivity reactions | GREENTHAL GMBH (DE) | 2003-04-30 | — | — | CN | disclosed |
| US-20030023100-A1 | Substituted pyrrole mannich bases to combat pain and allergic reactions | GRUENENTHAL GMBH (DE) | 2003-01-30 | — | — | US | disclosed |
| EP-1252166-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001042249-A1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM | EXXON CHEMICAL PATENTS INC. (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190006599-A1 | ORGANIC SEMICONDUCTING MATERIAL AND USE THEREOF IN ORGANIC DEVICES | CCNT1, CCNE2, EPCAM | GAA 2765/4885KDM4E 3376/4885LMNA 2909/4885 |
| US-20030023100-A1 | Substituted pyrrole mannich bases to combat pain and allergic reactions | CRHR1, CNR1, CRHR2 | GAA 487/4885KDM4E 3166/4885LMNA 4289/4885 |
| US-20060148796-A1 | 6-Substituted imidazopyrazines | VIP, GIPR, SI | GAA 1286/4885KDM4E 3312/4885LMNA 4442/4885 |
| US-11063222-B2 | Organic semiconducting material and use thereof in organic devices | CCNT1, CCNE2, EPCAM | GAA 2765/4885KDM4E 3376/4885LMNA 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.