Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MLLT3 | P42568 | 2/20 | 0.38 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27865369 | 0.95 | CHRNB4 (0.45) | OPRM1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL3173632 | 0.85 | DRD2 (0.42) | OPRM1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL4070124 | 0.81 | SLC18A3 (0.40) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL27900836 | 0.80 | OPRM1 (0.48) | OPRM1ESR1ESR2DRD2OPRK1 | |
| SCHEMBL27865382 | 0.78 | OPRM1 (0.46) | OPRM1CHRNB4CHRNA3DRD2 | |
| Biphenyl SCHEMBL27456670 | 0.77 | HRH3 (0.42) | — | |
| SCHEMBL27848437 | 0.77 | MAPT (0.45) | OPRM1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL27865371 | 0.75 | OPRM1 (0.49) | OPRM1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL3179200 | 0.75 | MAP2K7 (0.43) | OPRM1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL30241932 | 0.73 | CHRNB2 (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101091691-B | Keratin fibre dyeing composition containing 2, 3-diamino-6, 7-dihydro-1H, 5H-pyrazolo [1,2-a ] pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and substituted meta-aminophenol | OREAL | 2012-05-02 | — | — | CN | disclosed |