Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841663 | 0.85 | ALDH1A1 (0.35) | TSHRTPMT | |
| SCHEMBL918916 | 0.75 | TSHR (0.42) | TSHRHTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL14335016 | 0.72 | POLB (0.37) | TSHRHTR2AHTR2CHTR2BTPMT | |
| SCHEMBL8820615 | 0.71 | TPMT (0.41) | TSHRTPMTMAPK1 | |
| SCHEMBL13453368 | 0.70 | — | — | |
| SCHEMBL19126691 | 0.69 | GABRA1 (0.39) | TSHRHTR2AHTR2CHTR2BCES1 | |
| SCHEMBL28066512 | 0.68 | GRM1 (0.31) | — | |
| SCHEMBL10073283 | 0.67 | GABRA1 (0.42) | TSHRHTR2AHTR2CHTR2BCES1 | |
| SCHEMBL7289944 | 0.67 | KDM4E (0.38) | TSHRTPMT | |
| SCHEMBL5729444 | 0.66 | TSHR (0.35) | TSHRHTR2AHTR2CHTR2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103002740-B | Pesticidal combination | 先正达参股股份有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-103002731-B | Pesticidal combination | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-02 | — | — | CN | disclosed |
| CN-103002739-B | Methods for controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | CN | disclosed |
| CN-103002731-A | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-103002741-A | Method of crop enhancement | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-103002740-A | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-103002739-A | Methods for controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-102238871-A | Spiroheterocyclic n-oxyamides as pesticides | SYNGENTA PARTICIPATIONS AG | 2011-11-09 | — | — | CN | disclosed |