Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27849720 | 0.85 | TSHR (0.35) | TSHRTPMT | |
| SCHEMBL7289944 | 0.81 | KDM4E (0.38) | ALDH1A1KDM4EMAPTLMNATSHR | |
| SCHEMBL28175905 | 0.76 | TPMT (0.39) | ALDH1A1KDM4EMAPTTSHRTPMT | |
| SCHEMBL27713992 | 0.74 | TPMT (0.46) | ALDH1A1KDM4EMAPTLMNATSHR | |
| SCHEMBL6841351 | 0.74 | TDP1 (0.39) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL21259500 | 0.72 | SLC6A2 (0.38) | ALDH1A1KDM4EMAPTLMNAIGFBP3 | |
| SCHEMBL22298450 | 0.72 | SLC6A2 (0.38) | ALDH1A1KDM4EMAPTLMNAIGFBP3 | |
| SCHEMBL13453368 | 0.72 | — | — | |
| SCHEMBL7705523 | 0.71 | RAPGEF4 (0.39) | ALDH1A1KDM4EMAPTLMNATSHR | |
| SCHEMBL2848311 | 0.70 | RAPGEF4 (0.43) | ALDH1A1KDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103764634-B | N-epoxide pyrazolo-three azatropylidenes-derovatives | 先正达参股股份有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-103002740-B | Pesticidal combination | 先正达参股股份有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-103402979-B | Chemical compound | 先正达参股股份有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-103002731-B | Pesticidal combination | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-02 | — | — | CN | disclosed |
| CN-103002739-B | Methods for controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-09 | — | — | CN | disclosed |
| CN-103002731-A | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-103002739-A | Methods for controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-103002741-A | Method of crop enhancement | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-103002740-A | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2013-03-27 | — | — | CN | disclosed |
| CN-102245028-A | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG | 2011-11-16 | — | — | CN | disclosed |
| CN-102209469-A | Herbicidal compositions | SYNGENTA PARTICIPATIONS AG | 2011-10-05 | — | — | CN | disclosed |