Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 9/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL29875131 | 1.00 | CLTC (0.44) | CLTCCA1CA2CA12CA9 | |
| SCHEMBL28451650 | 0.86 | KMT2A (0.37) | CLTCCA1CA2CA12CA9 | |
| SCHEMBL28898006 | 0.85 | KMT2A (0.36) | CLTCCA1CA2CA12CA9 | |
| SCHEMBL13870630 | 0.79 | KMT2A (0.39) | CA1CA2CA12CA9MEN1 | |
| Lithium Ion SCHEMBL2890318 | 0.75 | CA1 (0.40) | CA1CA2CA12CA9CA7 | |
| SCHEMBL27851603 | 0.74 | NPC1 (0.42) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL28312087 | 0.72 | KMT2A (0.34) | CLTCMEN1USP2KMT2AKEAP1 | |
| SCHEMBL31305335 | 0.71 | CA1 (0.50) | CA1CA2CA12CA9MEN1 | |
| Potassium Ion SCHEMBL4636440 | 0.69 | CLTC (0.46) | CLTCMEN1KMT2A | |
| Potassium Ion SCHEMBL31670338 | 0.69 | CLTC (0.46) | CLTCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2755 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275693-A1 | MODIFIED WOUND DRESSINGS | CONVATEC TECHNOLOGIES INC. | 2021-09-09 | — | — | US | claimed |
| US-10961571-B2 | Polymerase assay with a FRET substrate | Life Technologies Corporation (US) | 2021-03-30 | — | — | US | claimed |
| US-20200400663-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | DXGEN CORP. (KR) | 2020-12-24 | — | — | US | claimed |
| EP-3726215-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | DxGen Corp. (KR) | 2020-10-21 | — | — | EP | claimed |
| EP-3174953-B1 | ENVIRONMENTALLY RESPONSIVE CHROMATIC LUMINESCENT COMPOSITIONS WITH IMPROVED HAND | BAMBU VAULT LLC (US) | 2020-09-02 | — | — | EP | claimed |
| US-20190307904-A1 | MODIFIED WOUND DRESSINGS | CONVATEC TECHNOLOGIES INC (US) | 2019-10-10 | — | — | US | claimed |
| EP-3541960-A2 | METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS | Quest Diagnostics Investments LLC (US) | 2019-09-25 | — | — | EP | claimed |
| EP-3066464-B1 | TEST DEVICE FOR DETECTING THE PRESENCE OR ABSENCE OF AN ANALYTE IN A LIQUID SAMPLE, AND PRODUCTION METHOD | JOANNEUM RES FORSCHUNGSGMBH (AT) | 2019-09-18 | — | — | EP | claimed |
| US-20190276904-A1 | METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS | QUEST DIAGNOSTICS INVESTMENTS LLC (US) | 2019-09-12 | — | — | US | claimed |
| WO-2019117586-A1 | SILICA NANOPARTICLES FOR BIOMARKER DIAGNOSIS AND METHOD FOR PRODUCING SAME | 주식회사 딕스젠 | 2019-06-20 | — | — | WO | claimed |
| WO-2005035794-A2 | DETECTION OF PRRSV | TETRACORE, INC. (US) | 2005-04-21 | — | — | WO | claimed |
| EP-1427854-A1 | METHODS FOR QUANTIFYING NUCLEAR RUN-ON TRANSCRIPTIONAL ASSAYS | Benitec Australia Ltd. (AU) | 2004-06-16 | — | — | EP | claimed |
| US-6653146-B1 | Detecting biological material (blood, fats, proteins) on medical instruments by applying a dye, exposing to ultraviolet light and observing for fluorescence; use in cleaning before sterilization | CHEMCLEAN CORPORATION | 2003-11-25 | — | — | US | claimed |
| WO-2003018832-A1 | METHODS FOR QUANTIFYING NUCLEAR RUN-ON TRANSCRIPTIONAL ASSAYS | BENITEC AUSTRALIA LTD (AU) | 2003-03-06 | — | — | WO | claimed |
| WO-2001036663-A9 | BIO-BURDEN VISUALIZATION SYSTEM | CHEMCLEAN CORP (US) | 2002-08-29 | — | — | WO | claimed |
| WO-2001036663-A2 | BIO-BURDEN VISUALIZATION SYSTEM | CHEMCLEAN CORPORATION (US) | 2001-05-25 | — | — | WO | claimed |
| EP-0870063-B1 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | PERKIN ELMER CORP (US) | 2000-07-26 | — | — | EP | claimed |
| EP-0870063-A2 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | THE PERKIN-ELMER CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| US-5716784-A | Fluorescence detection assay for homogeneous PCR hybridization systems | THE PERKIN-ELMER CORPORATION (US) | 1998-02-10 | — | — | US | claimed |
| WO-1997029210-A2 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | THE PERKIN-ELMER CORPORATION (US) | 1997-08-14 | — | — | WO | claimed |