Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851944 | 0.92 | CFD (0.33) | CFDADRB2HTR1ASLC6A2HTR2A | |
| SCHEMBL27851996 | 0.90 | CFD (0.33) | CFDADRB2HTR1ASLC6A2HTR2A | |
| SCHEMBL2444480 | 0.80 | ALDH1A1 (0.43) | CFDSLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL27851930 | 0.75 | SYK (0.35) | CFDSLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL29260070 | 0.70 | TPSAB1 (0.37) | CFDADRB2HTR1ASLC6A2HTR2A | |
| SCHEMBL29260071 | 0.70 | TPSAB1 (0.37) | CFDADRB2HTR1ASLC6A2HTR2A | |
| SCHEMBL15571986 | 0.68 | SLC6A2 (0.39) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL2921129 | 0.68 | SLC6A2 (0.43) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL30275082 | 0.68 | SLC6A2 (0.43) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 | |
| SCHEMBL1655323 | 0.68 | ADRA2C (0.42) | ADRB2HTR1ASLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102453001-A | Thiomorpholine compound and preparation method and application thereof | INST MATERIA MEDICA CAMS | 2012-05-16 | — | — | CN | disclosed |