Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786452 | 0.87 | MAPT (0.46) | ALDH1A1KDM4EMAPTLMNARAB9A | |
| SCHEMBL2785840 | 0.86 | NOX1 (0.36) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL2783769 | 0.84 | USP2 (0.36) | ALDH1A1KDM4EMAPTLMNARAB9A | |
| SCHEMBL2785719 | 0.82 | AURKB (0.42) | ALDH1A1KDM4EMAPTLMNARAB9A | |
| SCHEMBL2784439 | 0.81 | KIT (0.39) | ALDH1A1KDM4EMAPTLMNAAURKB | |
| SCHEMBL2787017 | 0.79 | MAPT (0.43) | ALDH1A1KDM4EMAPTLMNARAB9A | |
| SCHEMBL2770798 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL2787210 | 0.78 | KIT (0.41) | ALDH1A1KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL2785945 | 0.77 | MAPT (0.36) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL2784783 | 0.77 | MAPT (0.39) | ALDH1A1KDM4EMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |