Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787210 | 0.90 | KIT (0.41) | MAPTSMN1; SMN2TP53KITKDR | |
| SCHEMBL2784783 | 0.89 | MAPT (0.39) | MAPTSMN1; SMN2TP53KDM4ENPC1 | |
| SCHEMBL2785840 | 0.89 | NOX1 (0.36) | MAPTSMN1; SMN2TP53KITKDR | |
| SCHEMBL2785719 | 0.89 | AURKB (0.42) | MAPTSMN1; SMN2TP53KITKDR | |
| SCHEMBL2784439 | 0.83 | KIT (0.39) | MAPTTP53KITKDRHIF1A | |
| SCHEMBL2786452 | 0.83 | MAPT (0.46) | MAPTSMN1; SMN2TP53KITKDR | |
| SCHEMBL2783769 | 0.82 | USP2 (0.36) | MAPTSMN1; SMN2TP53HIF1AKDM4E | |
| SCHEMBL2785205 | 0.79 | ALDH1A1 (0.38) | MAPTSMN1; SMN2TP53HIF1AKDM4E | |
| SCHEMBL2785125 | 0.77 | MAPT (0.35) | MAPTSMN1; SMN2TP53KITKDR | |
| SCHEMBL2768714 | 0.77 | CYP1A2 (0.48) | MAPTSMN1; SMN2KITKDRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |