SCHEMBL278537

SCHEMBL278537

C=CCC(O)C(=C)C(=O)OCCOC(=O)C(=C)C(O)CC=C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TP53 P04637 2/20 0.33
TSHR P16473 2/20 0.33
HIF1A Q16665 2/20 0.33
THRB P10828 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22325457 0.91 THRB (0.33) TSHRTHRB
SCHEMBL5382707 0.86 TSHR (0.37) ALDH1A1TSHRHSD17B10
SCHEMBL22325461 0.82 THRB (0.55) ALDH1A1TSHRTHRBHSD17B10
SCHEMBL1618354 0.77 TSHR (0.37) ALDH1A1TP53TSHRHIF1ATHRB
SCHEMBL8658260 0.77 ALDH1A1 (0.53) ALDH1A1TP53
SCHEMBL6450262 0.74 THRB (0.38) ALDH1A1TSHRTHRB
SCHEMBL31199 0.74 CYP2C19 (0.39) HSD17B10
SCHEMBL902141 0.74 CYP2C19 (0.39) HSD17B10
SCHEMBL3888700 0.73 TSHR (0.44) TSHR
SCHEMBL10409187 0.71 TDP1 (0.33) ALDH1A1TP53TSHRHIF1ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11376813-B2 Composite article and related methods ND INDUSTRIES, INC. (US) 2022-07-05 US disclosed
WO-2018217968-A1 COMPOSITE ARTICLE AND RELATED METHODS ND INDUSTRIES, INC. (US) 2018-11-29 WO disclosed
US-20180339489-A1 COMPOSITE ARTICLE AND RELATED METHODS H.B. FULLER COMPANY 2018-11-29 US disclosed
US-8133420-B2 reinforce, insulating cavities in structural elements, by inserting at least two segments of solid polymers, each has different thermal expansion, one segment forming barrier which constrains expansion of other segment; low density polyethylene, ethylene/butyl acrylate/glycidyl methacrylate interpolymer DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-13 US disclosed
EP-2052015-A1 MULTI-SEGMENT EXPANDABLE POLYMER COMPOSITIONS WHICH EXPAND IN A CONTROLLABLE DIRECTION Dow Global Technologies Inc. (US) 2009-04-29 EP disclosed
EP-2004739-A2 ADHESION-MODIFIED EXPANDABLE POLYOLEFIN COMPOSITIONS AND INSULATED VEHICLE PARTS CONTAINING EXPANDED ADHESION-MODIFIED POLYOLEFIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2008-12-24 EP disclosed
US-20080075864-A1 Multi-segment expandable polymer compositions which expand in a controllable direction DOW GLOBAL TECHNOLOGIES INC. 2008-03-27 US disclosed
WO-2008021200-A1 MULTI-SEGMENT EXPANDABLE POLYMER COMPOSITIONS WHICH EXPAND IN A CONTROLLABLE DIRECTION DOW GLOBAL TECHNOLOGIES, INC. (US) 2008-02-21 WO disclosed
US-20070265364-A1 Adhesion-modified expandable polyolefin compositions and insulated vehicle parts containing expanded adhesion-modified polyolefin compositions ONER-DELIOMANLI DIDEM 2007-11-15 US disclosed
US-20070249743-A1 Expandable polyolefin compositions and insulated vehicle parts containing expanded polyolefin compositions DOW GLOBAL TECHNOLOGIES LLC 2007-10-25 US disclosed
WO-2007117664-A2 ADHESION-MODIFIED EXPANDABLE POLYOLEFIN COMPOSITIONS AND INSULATED VEHICLE PARTS CONTAINING EXPANDED ADHESION-MODIFIED POLYOLEFIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES, INC. (US) 2007-10-18 WO disclosed