SCHEMBL5382707

SCHEMBL5382707

C=CCOC(=O)C(=C)C(O)CC=C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278537 0.86 ALDH1A1 (0.33) TSHRALDH1A1HSD17B10
SCHEMBL770455 0.79 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL10409099 0.79 TSHR (0.36) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL3258226 0.79 GRIK1 (0.38) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL22325457 0.79 THRB (0.33) TSHR
SCHEMBL4555790 0.78 TDP1 (0.42) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL1260841 0.78 CYP3A4 (0.36) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL29027440 0.78 TSHR (0.40) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL5058288 0.76 TDP1 (0.43) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL8991844 0.76 CYP3A4 (0.37) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1832571-A1 Process for producing hydroxyl group-containing vinyl compound FUJIFILM Corporation (JP) 2007-09-12 EP disclosed
US-4873023-A HEATING A VERSATIC ESTER OF 1,3- OR 2,3-DIHYDROXYPROP-2 OR 1-YL ACRYLATE USING AN ESTERIFICATION CATALYST BASF AKTIENGESELLSCHAFT (DE) 1989-10-10 US disclosed