Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27897206 | 0.76 | GPR52 (0.47) | CES2CES1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL1697544 | 0.76 | ALDH1A1 (0.69) | CES2CES1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL29884110 | 0.76 | ALDH1A1 (0.69) | CES2CES1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL24609171 | 0.75 | CES2 (0.43) | CES2CES1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL262669 | 0.74 | ALDH1A1 (0.52) | CES2CES1ALDH1A1MEN1TP53 | |
| SCHEMBL19792666 | 0.74 | ALDH1A1 (0.52) | CES2CES1ALDH1A1MEN1TP53 | |
| Benzene SCHEMBL28264641 | 0.74 | ALDH1A1 (0.52) | CES2CES1ALDH1A1MEN1TP53 | |
| SCHEMBL950633 | 0.74 | ALDH1A1 (0.52) | CES2CES1ALDH1A1MEN1TP53 | |
| SCHEMBL3007220 | 0.74 | KDM4E (0.56) | CES2CES1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL13645552 | 0.74 | CES2 (0.46) | CES2CES1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102480932-A | Gut flora-derived extracellular vesicles, and method for searching for a disease model, vaccine, and candidate drug and for diagnosis using same | AEON MEDIX INC | 2012-05-30 | — | — | CN | claimed |
| CN-102480932-B | Gut flora-derived extracellular vesicles, and method for searching for a disease model, vaccine, and candidate drug and for diagnosis using same | AEON MEDIX INC | 2015-01-14 | — | — | CN | disclosed |
| CN-102480932-A | Gut flora-derived extracellular vesicles, and method for searching for a disease model, vaccine, and candidate drug and for diagnosis using same | AEON MEDIX INC | 2012-05-30 | — | — | CN | disclosed |