Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429925 | 0.89 | MGAM (0.46) | MGAMGAASIMGAM2CYP2C19 | |
| SCHEMBL11434419 | 0.83 | MGAM (0.46) | MGAMGAASIMGAM2CYP2C19 | |
| SCHEMBL25171670 | 0.82 | GAA (0.37) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL24214077 | 0.78 | ADRA2A (0.40) | CYP2C19L3MBTL1 | |
| SCHEMBL27436791 | 0.78 | MGAM (0.32) | MGAMGAASIMGAM2CYP2C19 | |
| SCHEMBL27895694 | 0.77 | GAA (0.30) | GAA | |
| SCHEMBL29021423 | 0.77 | MIF (0.36) | CYP2C19L3MBTL1 | |
| SCHEMBL10854964 | 0.77 | CYP2C19 (0.56) | CYP2C19L3MBTL1FAAH | |
| SCHEMBL6792231 | 0.77 | NAAA (0.50) | GAACYP2C19L3MBTL1 | |
| SCHEMBL1247793 | 0.77 | MGAM (0.39) | MGAMGAASIMGAM2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108605-A | Azaindole derivatives having AMPK activating effect | 盐野义制药株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-106413710-A | Factor xia inhibitors | 默沙东公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-1946680-B | Non-nucleoside reverse transcriptase inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 2011-04-06 | — | — | CN | disclosed |