SCHEMBL6429925

SCHEMBL6429925

CC(C)(C)CCOC(=O)CC(=O)OCCC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
CYP2C19 P33261 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
FAAH O00519 1/20 0.34
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
EGFR P00533 1/20 0.33
NAAA Q02083 1/20 0.32
DGKA P23743 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11434419 0.89 MGAM (0.46) MGAMGAASIMGAM2CYP2C19
SCHEMBL27854343 0.89 MGAM (0.36) MGAMGAASIMGAM2CYP2C19
SCHEMBL24214077 0.84 ADRA2A (0.40) CYP2C19L3MBTL1ADRA2AADRA1AMAPT
SCHEMBL27436791 0.83 MGAM (0.32) MGAMGAASIMGAM2CYP2C19
SCHEMBL6792231 0.83 NAAA (0.50) GAACYP2C19L3MBTL1BLMNAAA
SCHEMBL29021423 0.83 MIF (0.36) CYP2C19L3MBTL1ADRA2AADRA1AMAPT
SCHEMBL10854964 0.83 CYP2C19 (0.56) CYP2C19L3MBTL1ADRA2AADRA1AFAAH
SCHEMBL24630436 0.82 TDP1 (0.34) GAACYP2C19L3MBTL1EGFR
SCHEMBL6791519 0.81 CYP2C19 (0.34) CYP2C19L3MBTL1ADRA2AADRA1AMAPT
SCHEMBL5500580 0.81 DGKA (0.48) ADRA2AADRA1AMAPTBLMDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119585252-A Bicyclic heteroaryl containing compounds as IKZF2 degrading agents 翁科皮亚治疗公司和SK生命科学实验室 2025-03-07 CN disclosed
WO-2025047490-A1 GAS SEPARATION MEMBRANE AND METHOD FOR PRODUCING GAS SEPARATION MEMBRANE 株式会社ダイセル 2025-03-06 WO disclosed
WO-2025028075-A1 TWO-PACK TYPE RESIN COMPOSITION 株式会社日本触媒 2025-02-06 WO disclosed
CN-119278199-A Kinesin KIF18A inhibitor and application thereof 上海湃隆生物科技有限公司 2025-01-07 CN disclosed
CN-116323837-B Polyurethane curing agent and application thereof 旭化成株式会社 2024-10-25 CN disclosed
CN-115916777-B ATX inhibitor and preparation method and application thereof 苏州爱科百发生物医药技术有限公司 2024-07-12 CN disclosed
CN-115335369-B GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof 克林提克斯医药股份有限公司 2024-07-02 CN disclosed
CN-118271261-A Dicarbonyl compound containing cyclobutane segment and synthesis method thereof 中国科学技术大学 2024-07-02 CN disclosed
EP-3771720-B1 BLOCKED POLYISOCYANATE COMPOSITION, RESIN COMPOSITION, RESIN FILM AND LAMINATE ASAHI CHEMICAL IND (JP) 2024-05-01 EP disclosed
CN-111868051-B Aminopyrimidine derivatives as CTPS1 inhibitors 斯泰普制药股份公司 2024-04-09 CN disclosed
US-6897306-B2 3-heterocyclylpropanohydroxamic acids PFIZER PRODUCTS, INC. (US) 2005-05-24 US disclosed
EP-1240152-B1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-08 EP disclosed
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids BAILEY SIMON (US) 2003-06-26 US disclosed
EP-1240152-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS Pfizer Limited (GB) 2002-09-18 EP disclosed
US-6448278-B2 ANTISCARRING AGENT PFIZER INC. 2002-09-10 US disclosed
US-20010021718-A1 Procollagen C-proteinase inhibitors PFIZER INC. 2001-09-13 US disclosed
WO-2001047901-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LIMITED (GB) 2001-07-05 WO disclosed
US-5229243-A Addition polymer core, polyurethane or polythiourethane shell KAO CORPORATION (JP) 1993-07-20 US disclosed
EP-0501673-A1 Encapsulated toner for heat pressure fixing Kao Corporation (JP) 1992-09-02 EP disclosed
US-4596883-A Herbicidally active substituted diphenyl ethers PPG INDUSTRIES, INC. (US) 1986-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010021718-A1 Procollagen C-proteinase inhibitors MMP1, CTSL, PREP MGAM 312/4885GAA 1264/4885SI 195/4885
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids CPA1, MMP1, PREP MGAM 575/4885GAA 887/4885SI 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.