SCHEMBL6792231

SCHEMBL6792231

CCC(=O)OCCC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.50
GAA P10253 1/20 0.39
HTT P42858 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 1/20 0.36
HPGD P15428 1/20 0.36
BLM P54132 1/20 0.36
WRN Q14191 1/20 0.36
HIF1A Q16665 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TRPA1 O75762 1/20 0.36
DGKA P23743 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14296149 0.86 NAAA (0.57) NAAAGAAHTTALDH1A1CYP2C19
SCHEMBL8581054 0.84 NAAA (0.48) NAAAGAAHTTALDH1A1CYP2C19
SCHEMBL6429925 0.83 MGAM (0.46) NAAAGAACYP2C19BLMDGKA
SCHEMBL8340130 0.82 DGKA (0.47) NAAAALDH1A1BLMDGKA
SCHEMBL10854964 0.81 CYP2C19 (0.56) NAAAALDH1A1CYP2C19BLMTRPA1
SCHEMBL29021423 0.81 MIF (0.36) NAAAALDH1A1CYP2C19BLMTRPA1
SCHEMBL19350278 0.80 NAAA (0.45) NAAAGAAHTTALDH1A1CYP2C19
SCHEMBL20512190 0.80 NAAA (0.45) NAAAGAAHTTALDH1A1CYP2C19
SCHEMBL136377 0.80 NAAA (0.45) NAAAGAAHTTALDH1A1CYP2C19
SCHEMBL5500580 0.79 DGKA (0.48) CYP1A2BLMDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115175735-B Antiviral compounds 吉利德科学公司 2025-03-04 CN disclosed
US-11786605-B2 Site specific antibody-drug conjugates with peptide-containing linkers MERSANA THERAPEUTICS, INC. (US) 2023-10-17 US disclosed
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES ASANA BIOSCIENCES, LLC 2023-06-15 US disclosed
WO-2022030469-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM 日産化学株式会社 2022-02-10 WO disclosed
WO-2022030468-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM 日産化学株式会社 2022-02-10 WO disclosed
US-20180154018-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2018-06-07 US disclosed
US-20180140716-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2018-05-24 US disclosed
US-9943609-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2018-04-17 US disclosed
US-9872918-B2 Hydroxyl-polymer-drug-protein conjugates MERSANA THERAPEUTICS, INC. (US) 2018-01-23 US disclosed
US-9849191-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2017-12-26 US disclosed
US-7671095-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2010-03-02 US disclosed
US-20090156800-A1 PROCESS FOR MAKING MACROCYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2009-06-18 US disclosed
US-20080181868-A1 MACROCYLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2008-07-31 US disclosed
US-20080075718-A1 Films and Particles THE TRUSTEES OF THE BOSTON UNIVERSITY 2008-03-27 US disclosed
US-20080075718-A1 Films and Particles THE TRUSTEES OF THE BOSTON UNIVERSITY 2008-03-27 US disclosed
US-20070281885-A1 MACROCYLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2007-12-06 US disclosed
US-20040248981-A1 Benzamidine derivatives SANKYO COMPANY, LIMITED (JP) 2004-12-09 US disclosed
US-20040010009-A1 Benzamidine derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-15 US disclosed
US-6555556-B1 N-(4-(1-acetimidoylpiperidin-4-yl)oxyphenyl)-N-((E)-3-(3 -amidinophenyl)-2-methyl-2-propenyl)sulfamoylacetic acid dihydrochloride for example; factor Xa inhibitors SANKYO COMPANY, LIMITED (JP) 2003-04-29 US disclosed
EP-1245564-A1 BENZAMIDINE DERIVATIVES Sankyo Company, Limited (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080181868-A1 MACROCYLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS HCCS, CPN1, HPN NAAA 1685/4885GAA 630/4885HTT 4160/4885
US-20230183326-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO NAAA 3020/4885GAA 2569/4885HTT 4197/4885
US-20070281885-A1 MACROCYLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS HCCS, CPN1, HPN NAAA 1685/4885GAA 630/4885HTT 4160/4885
US-20180140716-A1 PROTEIN-POLYMER-DRUG CONJUGATES PBRM1, STAMBP, TSPO NAAA 3020/4885GAA 2569/4885HTT 4197/4885
US-20080075718-A1 Films and Particles APOB, PGF, ACTB NAAA 3310/4885GAA 836/4885HTT 581/4885
US-11786605-B2 Site specific antibody-drug conjugates with peptide-containing linkers CD2BP2, DNPEP, LNPEP NAAA 2915/4885GAA 814/4885HTT 4091/4885
US-20040010009-A1 Benzamidine derivatives HABP2, F7, F2 NAAA 145/4885GAA 1042/4885HTT 2874/4885
US-20040248981-A1 Benzamidine derivatives HABP2, F7, F2 NAAA 140/4885GAA 997/4885HTT 2865/4885
US-20090156800-A1 PROCESS FOR MAKING MACROCYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS PREP, HCCS, PEPD NAAA 1048/4885GAA 426/4885HTT 3278/4885
US-20180154018-A1 PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES CD2BP2, DNPEP, LNPEP NAAA 2654/4885GAA 834/4885HTT 3239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.