SCHEMBL27855832

SCHEMBL27855832

O=S(=O)(O)c1ccc(C(F)(F)F)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.47
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PDE2A O00408 1/20 0.46
MCL1 Q07820 5/20 0.44
CDK1 P06493 1/20 0.44
CCNB1 P14635 1/20 0.44
CCNA2 P20248 1/20 0.44
CCND1 P24385 1/20 0.44
CDK2 P24941 1/20 0.44
CDK7 P50613 1/20 0.44
CCNH P51946 1/20 0.44
CCNA1 P78396 1/20 0.44
CDK6 Q00534 1/20 0.44
HSD11B1 P28845 3/20 0.43
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28078954 0.98 MRGPRX4 (0.46) MRGPRX4MEN1ALDH1A1TSHRKMT2A
Anthraquinone SCHEMBL28556111 0.89 MCL1 (0.44) MRGPRX4MEN1ALDH1A1TSHRKMT2A
SCHEMBL27855804 0.85 ALDH1A1 (0.58) MRGPRX4MEN1ALDH1A1TSHRKMT2A
SCHEMBL23084667 0.83 CYP2C19 (0.45) ALDH1A1L3MBTL1HSD11B1CA1CA2
SCHEMBL29907293 0.83 TRPV4 (0.53) MEN1ALDH1A1TSHRKMT2AATM
SCHEMBL66378 0.83 TRPV4 (0.53) MEN1ALDH1A1TSHRKMT2AATM
SCHEMBL6038959 0.81 KIF11 (0.49) MEN1ALDH1A1TSHRKMT2AATM
SCHEMBL6038948 0.81 MEN1 (0.46) MEN1ALDH1A1TSHRKMT2AATM
SCHEMBL16770865 0.81 MCL1 (0.47) MEN1ALDH1A1TSHRKMT2AATM
SCHEMBL1767738 0.81 CA1 (0.53) MEN1ALDH1A1TSHRKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102482197-A Process for producing diquaternary ammonium salt and novel intermediate WAKO PURE CHEM IND LTD 2012-05-30 CN disclosed