Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27838566 | 1.00 | MAOA (0.40) | MAOAMAOBACHEPTGDRPTGDR2 | |
| SCHEMBL484798 | 0.86 | LMNA (0.44) | MAOAMAOBACHEPTGDRPTGDR2 | |
| SCHEMBL19521080 | 0.78 | KMT2A (0.54) | LMNAKMT2ACTSS | |
| SCHEMBL28300302 | 0.78 | PDPK1 (0.56) | MAOAMAOBACHEKMT2AEPHX2 | |
| SCHEMBL28224650 | 0.78 | PDPK1 (0.56) | MAOAMAOBACHEKMT2AEPHX2 | |
| SCHEMBL30985322 | 0.76 | PDPK1 (0.58) | MAOAMAOBACHEHTR2AHTR2C | |
| SCHEMBL805451 | 0.76 | HTR2A (0.46) | MAOAMAOBACHEHTR2AHTR2C | |
| SCHEMBL15447552 | 0.76 | PDPK1 (0.58) | MAOAMAOBACHEHTR2AHTR2C | |
| SCHEMBL6497708 | 0.76 | PDPK1 (0.58) | MAOAMAOBACHEHTR2AHTR2C | |
| SCHEMBL10469026 | 0.74 | FABP4 (0.43) | PTGDRPTGDR2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | disclosed |
| CN-102365276-A | Substituted spiro-amide compounds | GRUENENTHAL GMBH | 2012-02-29 | — | — | CN | disclosed |