Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985322 | 0.86 | PDPK1 (0.58) | HTR2AHTR2CHTR2BPDPK1MAOA | |
| SCHEMBL6497708 | 0.86 | PDPK1 (0.58) | HTR2AHTR2CHTR2BPDPK1MAOA | |
| SCHEMBL484798 | 0.77 | LMNA (0.44) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL19521127 | 0.76 | PDPK1 (0.46) | HTR2AHTR2CHTR2BPDPK1MAOA | |
| SCHEMBL27856416 | 0.76 | MAOA (0.40) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL27838566 | 0.76 | MAOA (0.40) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL24593559 | 0.76 | HTR2A (0.64) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| SCHEMBL3364642 | 0.76 | HTR2A (0.64) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| SCHEMBL20241214 | 0.73 | HTR2A (0.47) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| SCHEMBL23275508 | 0.72 | HTR2A (0.38) | HTR2AHTR2CHTR2BPDPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | HTR2A 475/4885HTR2C 549/4885HTR2B 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.