SCHEMBL27856432

SCHEMBL27856432

C=CCc1ccc2ccccc2n1.[AlH3]

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 2/20 0.47
CYSLTR2 Q9NS75 1/20 0.47
CYP1A2 P05177 2/20 0.44
NCF1 P14598 1/20 0.41
NOS2 P35228 1/20 0.41
BACE1 P56817 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
PDE10A Q9Y233 2/20 0.41
GPBAR1 Q8TDU6 1/20 0.39
LMNA P02545 1/20 0.39
KDM1A O60341 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322184 0.98 CYSLTR1 (0.49) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
Hydrochloric Acid SCHEMBL27834787 0.96 CYSLTR1 (0.47) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
Bromide SCHEMBL28854191 0.96 CYSLTR1 (0.47) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
Hydrogen Sulfide SCHEMBL27881046 0.96 CYSLTR1 (0.47) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
Quinoline SCHEMBL11076491 0.88 ALDH1A1 (0.55) CYSLTR1CYSLTR2CYP1A2PDE10AGPBAR1
SCHEMBL27956726 0.85 PDE10A (0.40) CYSLTR1CYSLTR2CYP1A2PDE10ALMNA
SCHEMBL6525088 0.82 CYSLTR1 (0.52) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL17227498 0.80 CYSLTR1 (0.50) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL5510083 0.79 CYSLTR1 (0.46) CYSLTR1CYSLTR2CYP1A2NCF1NOS2
SCHEMBL4128709 0.79 PDE10A (0.46) CYSLTR1CYSLTR2CYP1A2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102185109-A Preparation method of organic multilayer film INST OF MICROELECTRONICS CAS 2011-09-14 CN disclosed