Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27337700 | 0.89 | HDAC1 (0.53) | HDAC1POLBTACR1KMT2AKDM4E | |
| SCHEMBL28941358 | 0.79 | HDAC1 (0.50) | HDAC1POLBTACR1KMT2AKDM4E | |
| SCHEMBL23611190 | 0.78 | HDAC1 (0.46) | HDAC1POLBTACR1KMT2AKDM4E | |
| SCHEMBL1818475 | 0.78 | POLB (0.46) | HDAC1POLBKMT2AKDM4ELMNA | |
| SCHEMBL11789928 | 0.78 | LMNA (0.47) | HDAC1POLBKMT2AKDM4ELMNA | |
| SCHEMBL23611192 | 0.78 | HDAC1 (0.46) | HDAC1POLBTACR1KMT2AKDM4E | |
| SCHEMBL8706846 | 0.78 | CES2 (0.53) | HDAC1POLBTACR1KMT2AKDM4E | |
| SCHEMBL6508853 | 0.77 | ALDH1A1 (0.41) | TACR1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL17775467 | 0.77 | HDAC1 (0.48) | HDAC1POLBKMT2AKDM4ELMNA | |
| SCHEMBL11243117 | 0.76 | ROCK2 (0.49) | HDAC1POLBTACR1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102485743-A | Antineoplastic compound | BEIJING HANMEI PHARMACEUTICAL CO LTD | 2012-06-06 | — | — | CN | disclosed |