Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033980 | 0.86 | MAPT (0.52) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL29033968 | 0.86 | MAPT (0.41) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL27680977 | 0.86 | MEN1 (0.45) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL20630984 | 0.83 | CHEK1 (0.49) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL28242342 | 0.82 | AR (0.46) | MAPTMEN1POLBKMT2ANPSR1 | |
| SCHEMBL8782300 | 0.82 | MAPT (0.41) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL27844926 | 0.82 | MAPT (0.48) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL27825929 | 0.81 | MAPT (0.47) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL31443866 | 0.79 | CHEK1 (0.33) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL3014712 | 0.77 | MAPT (0.49) | MAPTMEN1POLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102250007-A | Preparation method of 3,4-binitropyrazole | UNIV NORTH CHINA | 2011-11-23 | — | — | CN | claimed |
| CN-102250007-A | Preparation method of 3,4-binitropyrazole | UNIV NORTH CHINA | 2011-11-23 | — | — | CN | disclosed |