Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825929 | 0.98 | MAPT (0.47) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL27858187 | 0.82 | MAPT (0.44) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL29033968 | 0.81 | MAPT (0.41) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL29033980 | 0.78 | MAPT (0.52) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL27708602 | 0.78 | CYP19A1 (0.52) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL27680977 | 0.75 | MEN1 (0.45) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL5264555 | 0.75 | ALDH1A1 (0.32) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL20630984 | 0.73 | CHEK1 (0.49) | MAPTTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3014712 | 0.73 | MAPT (0.49) | MAPTTDP1MEN1KMT2APOLB | |
| SCHEMBL28313237 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102336711-A | 4-amino-3,5-dinitropyrazole lead salt as well as preparation method and application thereof | XIAN MODERN CHEMISTRY RES INST | 2012-02-01 | — | — | CN | disclosed |
| CN-102250007-A | Preparation method of 3,4-binitropyrazole | UNIV NORTH CHINA | 2011-11-23 | — | — | CN | disclosed |