Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858187 | 0.86 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL29033968 | 0.82 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11740769 | 0.79 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1DHFR | |
| SCHEMBL27680977 | 0.79 | MEN1 (0.45) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL27844926 | 0.78 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL5992360 | 0.78 | VCAM1 (0.60) | MAPTMEN1KMT2AALDH1A1DHFR | |
| SCHEMBL27825929 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1829344 | 0.77 | AHR (0.50) | MAPTALDH1A1NPSR1 | |
| SCHEMBL20630984 | 0.77 | CHEK1 (0.49) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2461199 | 0.76 | VCAM1 (0.58) | MAPTMEN1KMT2AALDH1A1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444436-A | Synthesis method of aminophenylpyrazole compound | 曲靖师范学院 | 2023-07-18 | — | — | CN | disclosed |