Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517809 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4EENPP2CASP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL29951492 | 0.98 | ALDH1A1 (0.39) | ALDH1A1KDM4EENPP2CASP1CYP3A4 | |
| SCHEMBL1702676 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4EENPP2CASP1CYP3A4 | |
| SCHEMBL29631566 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4EENPP2CASP1CYP3A4 | |
| SCHEMBL28824845 | 0.77 | — | — | |
| SCHEMBL4963 | 0.76 | CA3 (0.48) | ALDH1A1 | |
| SCHEMBL29406861 | 0.76 | CA3 (0.48) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7248645 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EENPP2CASP1CYP3A4 | |
| SCHEMBL28730410 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EENPP2CASP1CYP3A4 | |
| SCHEMBL3328437 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4EENPP2CASP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | claimed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | claimed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | claimed |
| US-20080214912-A1 | Blood Glucose Monitoring System And Method | GLUCOSE SENSING TECHNOLOGIES, LLC (US) | 2008-09-04 | — | — | US | claimed |
| WO-2025108234-A1 | COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦药物研究院有限公司 | 2025-05-30 | — | — | WO | disclosed |
| CN-119954784-A | Compound, preparation method and application thereof | 四川科伦药物研究院有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119504808-A | Compound, preparation method and application thereof | 四川科伦药物研究院有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-118994567-A | Preparation and application of novel pH and glucose dual-response polymer and hydrogel | 南京工业大学 | 2024-11-22 | — | — | CN | disclosed |
| US-20240174660-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. | 2024-05-30 | — | — | US | disclosed |
| US-11905281-B2 | KRAS G12C inhibitors and methods of using the same | AMGEN INC. (US) | 2024-02-20 | — | — | US | disclosed |
| US-20240050430-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. | 2024-02-15 | — | — | US | disclosed |
| EP-3788038-B1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20110050431-A1 | Beverage containers with detection capability | GEARBOX, LLC | 2011-03-03 | — | — | US | disclosed |
| WO-2010072712-A1 | BIARYL BENZYLAMINE DERIVATIVES | NOVARTIS AG (CH) | 2010-07-01 | — | — | WO | disclosed |
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | ANGST DANIELA | 2010-07-01 | — | — | US | disclosed |
| US-20090142279-A1 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-06-04 | — | — | US | disclosed |
| US-20080214912-A1 | Blood Glucose Monitoring System And Method | GLUCOSE SENSING TECHNOLOGIES, LLC (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080051401-A1 | 2,4,6-Trisubstituted Pyrimidines as Phosphotidylinositol (Pi) 3-Kinase Inhibitors and Their Use in the Treatment of Cancer | PASS MARTIN | 2008-02-28 | — | — | US | disclosed |
| EP-1778681-A1 | 2,4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | AstraZeneca AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006005918-A1 | 2, 4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174660-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | KRAS, NRAS, HRAS | ALDH1A1 4162/4885KDM4E 4105/4885ENPP2 698/4885 |
| US-20090142279-A1 | NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | CHRM3, CHRM2, CHRNA3 | ALDH1A1 3228/4885KDM4E 3709/4885ENPP2 826/4885 |
| US-20240050430-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | KRAS, NRAS, HRAS | ALDH1A1 4162/4885KDM4E 4105/4885ENPP2 698/4885 |
| US-11905281-B2 | KRAS G12C inhibitors and methods of using the same | KRAS, NRAS, HRAS | ALDH1A1 4162/4885KDM4E 4105/4885ENPP2 698/4885 |
| US-20080051401-A1 | 2,4,6-Trisubstituted Pyrimidines as Phosphotidylinositol (Pi) 3-Kinase Inhibitors and Their Use in the Treatment of Cancer | PIK3CA, TYMP, PIK3CB | ALDH1A1 2649/4885KDM4E 1370/4885ENPP2 672/4885 |
| US-20100168079-A1 | Biaryl Benzylamine Derivatives | BRD3, BRD2, BBOX1 | ALDH1A1 1314/4885KDM4E 1108/4885ENPP2 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.