Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816524 | 0.79 | MAPT (0.59) | MAPTALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL7949126 | 0.76 | L3MBTL1 (0.58) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL27863288 | 0.75 | CRHBP (0.55) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL9538742 | 0.73 | MAPT (0.59) | MAPTALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL11661312 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL2874199 | 0.72 | LMNA (0.50) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL9116525 | 0.72 | MAPT (0.62) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL26654911 | 0.72 | ALDH1A1 (0.45) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL31457743 | 0.72 | ALDH1A1 (0.45) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL6820117 | 0.70 | HTR1A (0.51) | MAPTALDH1A1HPGDTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012512-A | GROWTH-PROMOTING AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |