SCHEMBL278635

SCHEMBL278635

O=C1NC(c2ccccc2)=C2C(=O)NC(c3ccccc3)=C12

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 7/20 0.48
PTGS2 P35354 5/20 0.47
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 1/20 0.41
PLA2G10 O15496 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91967 0.95 PTGS2 (0.48) GSK3BPTGS2ALDH1A1MAOAMAOB
SCHEMBL7754290 0.95 PTGS2 (0.48) GSK3BPTGS2ALDH1A1MAOAMAOB
SCHEMBL8502944 0.88 PTGS1 (0.46) GSK3BPTGS2KDM4EMAPT
SCHEMBL12577691 0.88 ALDH1A1 (0.52) GSK3BPTGS2ALDH1A1
SCHEMBL9833136 0.88 PTGS2 (0.47) GSK3BPTGS2ALDH1A1HPGDMAPT
SCHEMBL25027808 0.88 GSK3B (0.41) GSK3BPTGS2ALDH1A1
SCHEMBL1557806 0.88 GSK3B (0.54) GSK3BPTGS2KDM4EGAALMNA
SCHEMBL12577696 0.86 ALDH1A1 (0.56) GSK3BPTGS2ALDH1A1GAALMNA
SCHEMBL12640639 0.86 PTGS2 (0.42) GSK3BPTGS2ALDH1A1MAOAMAOB
SCHEMBL92072 0.86 CYP1A2 (0.56) GSK3BPTGS2KDM4EGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118630240-A Preparation method of platinum-carbon catalyst for proton exchange membrane fuel cell and platinum-carbon catalyst 陕西瑞科新材料股份有限公司 2024-09-10 CN claimed
CN-112940431-B Laser-induced fluorescence emission composition and patterned fluorescence emission method 四川大学 2023-03-10 CN claimed
CN-108493347-B Organic photoelectric detector with high light-dark current ratio and high light responsivity 合肥工业大学 2022-02-15 CN claimed
CN-112940431-A Laser-induced fluorescence emission composition and patterned fluorescence emission method 四川大学 2021-06-11 CN claimed
EP-1412431-B1 PIGMENT COMPOSITIONS AND PIGMENTED WATER-BASED COATING MATERIALS BASF SE (DE) 2014-05-14 EP claimed
EP-2303967-B1 IMPROVED, RED COLOUR FILTER COMPOSITION BASF SE (DE) 2013-11-13 EP claimed
US-8273269-B2 Red colour filter composition BASF SE (DE) 2012-09-25 US claimed
EP-1502932-B1 RESIN COMPOSITION SONY CORP (JP) 2012-07-11 EP claimed
EP-2261286-B1 Resin composition SONY CORP (JP) 2012-06-06 EP claimed
US-20110155973-A1 IMPROVED, RED COLOUR FILTER COMPOSITION BASF SE (DE) 2011-06-30 US claimed
EP-0719842-A2 Pigment compositions for coatings CIBA-GEIGY AG (CH) 1996-07-03 EP claimed
US-5529623-A Pigmentary solid solutions of pyrrolo[3,4-c]pyrroles and quinacridones CIBA-GEIGY CORPORATION (US) 1996-06-25 US claimed
EP-0704496-A1 Pigmentary solid solutions of pyrrolo 3,4-C pyrroles and quinacridones CIBA-GEIGY AG (CH) 1996-04-03 EP claimed
EP-0696620-A1 Solid solutions of pyrrolo- 3,4-c -pyrroles with quinacridonequinones CIBA-GEIGY AG (CH) 1996-02-14 EP claimed
US-5472496-A Ternery component; light and weatherfastness; useful as colorant in plastics, inks and automotive paints CIBA-GEIGY CORPORATION (US) 1995-12-05 US claimed
US-RE35009-E Diketopyrrolopyrrole pigments in platelet form CIBA-GEIGY CORPORATION (US) 1995-08-01 US claimed
EP-0408498-B1 Plate like organic effect pigments CIBA GEIGY AG (CH) 1994-09-14 EP claimed
EP-0232222-B1 Process for the preparation of brominated pyrrolo-[3,4-c]-pyrroles CIBA-GEIGY AG (CH) 1992-09-09 EP claimed
US-5095122-A DIKETOPYRROLOPYRROLE PIGMENTS IN PLATELET FORM CIBA-GEIGY CORPORATION (US) 1992-03-10 US claimed
EP-0408498-A2 Plate like organic effect pigments CIBA-GEIGY AG (CH) 1991-01-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110155973-A1 IMPROVED, RED COLOUR FILTER COMPOSITION NR2E3, MRPS22, NR2C2 GSK3B 4269/4885PTGS2 1298/4885ALDH1A1 3868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.