Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320663 | 0.88 | TRPM2 (0.64) | NPC1RAB9ATRPV1MAPTNAMPT | |
| SCHEMBL4185773 | 0.88 | TRPM2 (0.64) | NPC1RAB9ATRPV1MAPTNAMPT | |
| SCHEMBL4185775 | 0.88 | TRPM2 (0.64) | NPC1RAB9ATRPV1MAPTNAMPT | |
| SCHEMBL30387813 | 0.88 | TRPM2 (0.64) | NPC1RAB9ATRPV1MAPTNAMPT | |
| SCHEMBL15651315 | 0.83 | BTK (0.54) | BTKNPC1RAB9ATRPV1MAPT | |
| SCHEMBL15651317 | 0.83 | BTK (0.54) | BTKNPC1RAB9ATRPV1MAPT | |
| SCHEMBL13352236 | 0.81 | MMP1 (0.72) | NPC1RAB9ATRPV1MAPTNAMPT | |
| SCHEMBL25722352 | 0.79 | NPC1 (0.59) | NPC1RAB9ATRPV1MAPTNAMPT | |
| SCHEMBL2705335 | 0.78 | NAMPT (0.53) | NPC1RAB9AMAPTNAMPTEGFR | |
| SCHEMBL10054867 | 0.78 | NAMPT (0.53) | NPC1RAB9AMAPTNAMPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102421754-A | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO LTD | 2012-04-18 | — | — | CN | disclosed |