Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875436 | 0.83 | BRD4 (0.40) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL22130941 | 0.79 | AKT1 (0.32) | L3MBTL1PAX8TDP1ALDH1A1TSHR | |
| SCHEMBL13144272 | 0.75 | KMT2A (0.48) | MEN1KMT2ANPSR1CYP3A4CYP2C9 | |
| SCHEMBL8736767 | 0.75 | MEN1 (0.43) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL504005 | 0.75 | L3MBTL1 (0.55) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL7363893 | 0.74 | KDM4E (0.45) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL7200107 | 0.74 | RAB9A (0.57) | MEN1KMT2ANPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL28774233 | 0.74 | NPSR1 (0.39) | MEN1KMT2ANPSR1CYP3A4CYP2C9 | |
| SCHEMBL2354804 | 0.73 | L3MBTL1 (0.43) | MEN1KMT2ANPSR1RAB9ACYP3A4 | |
| SCHEMBL8782785 | 0.73 | MEN1 (0.41) | MEN1KMT2ANPSR1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102432529-B | Preparation method of styryl pyridine disulfide dinitrogen derivative | JIANGSU INST NUCLEAR MEDICINE | 2014-03-26 | — | — | CN | claimed |
| CN-102432529-A | Styryl pyridine disulfide dinitrogen derivative and preparation method thereof | JIANGSU INST NUCLEAR MEDICINE | 2012-05-02 | — | — | CN | claimed |
| CN-102432529-B | Preparation method of styryl pyridine disulfide dinitrogen derivative | JIANGSU INST NUCLEAR MEDICINE | 2014-03-26 | — | — | CN | disclosed |
| CN-102432529-A | Styryl pyridine disulfide dinitrogen derivative and preparation method thereof | JIANGSU INST NUCLEAR MEDICINE | 2012-05-02 | — | — | CN | disclosed |