Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738099 | 0.90 | ALOX15 (0.49) | KMT2AALDH1A1MEN1ALOX15GFER | |
| SCHEMBL10881708 | 0.82 | PTGS2 (0.52) | ALDH1A1ALOX15GFERADAM17LMNA | |
| SCHEMBL28243247 | 0.80 | PTGS2 (0.50) | ALDH1A1ALOX15GFERADAM17LMNA | |
| SCHEMBL11014337 | 0.79 | ALOX15 (0.49) | KMT2AALDH1A1MEN1ALOX15GFER | |
| SCHEMBL184737 | 0.79 | ROCK1 (0.47) | MAPTKMT2AALDH1A1MEN1TEAD4 | |
| SCHEMBL27870340 | 0.78 | ALDH1A1 (0.43) | MAPTKMT2AALDH1A1MEN1TEAD4 | |
| SCHEMBL185920 | 0.78 | ALDH1A1 (0.56) | MAPTKMT2AALDH1A1MEN1TEAD4 | |
| SCHEMBL9272487 | 0.77 | MAPT (0.51) | MAPTKMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL4124118 | 0.75 | KMT2A (0.69) | MAPTKMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL8834358 | 0.74 | PARP10 (0.44) | MAPTKMT2AMEN1ACACBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414177-B | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT | 2014-07-02 | — | — | CN | disclosed |
| CN-102414177-A | Compounds as bradykinin b1 antagonists | BOEHRINGER INGELHEIM INT | 2012-04-11 | — | — | CN | disclosed |