Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.43 |
| ▸ | MDH1 | P40925 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870538 | 0.90 | CACNA1G (0.46) | FAAH | |
| SCHEMBL27870537 | 0.89 | ATM (0.43) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10277098 | 0.79 | NPY2R (0.42) | MEN1KMT2AFAAH | |
| SCHEMBL10276804 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL10276801 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL5546576 | 0.74 | L3MBTL1 (0.62) | L3MBTL1KDM4EALDH1A1PPARDPPARA | |
| SCHEMBL27853811 | 0.72 | HTT (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27853844 | 0.71 | TP53 (0.35) | KDM4EALDH1A1KMT2A | |
| SCHEMBL23632422 | 0.70 | MAPT (0.63) | L3MBTL1KDM4EALDH1A1PPARDPPARA | |
| SCHEMBL25860142 | 0.70 | KDM4E (0.65) | L3MBTL1KDM4EALDH1A1PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471260-B | Novel benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-10-22 | — | — | CN | disclosed |
| CN-102471260-A | Novel benzenesulfonamide compounds, process for their synthesis and their use in pharmaceuticals and cosmetics | GALDERMA RES & DEV | 2012-05-23 | — | — | CN | disclosed |