Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870538 | 0.90 | CACNA1G (0.46) | FAAHMAPK1 | |
| SCHEMBL27870544 | 0.89 | L3MBTL1 (0.47) | FAAHALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10276804 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10276801 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10277098 | 0.79 | NPY2R (0.42) | ATMFAAHMEN1KMT2A | |
| SCHEMBL27853844 | 0.73 | TP53 (0.35) | ATMSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL2858333 | 0.72 | TP53 (0.58) | ATMFAAHSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27853811 | 0.72 | HTT (0.32) | ATMALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL30443787 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9610831 | 0.69 | LMNA (0.53) | SMN1; SMN2ALDH1A1LMNADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471260-B | Novel benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-10-22 | — | — | CN | disclosed |
| CN-102471260-A | Novel benzenesulfonamide compounds, process for their synthesis and their use in pharmaceuticals and cosmetics | GALDERMA RES & DEV | 2012-05-23 | — | — | CN | disclosed |