Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24961299 | 0.78 | CYP1A2 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL215469 | 0.77 | PLA2G7 (0.65) | PLA2G7ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL215470 | 0.77 | PLA2G7 (0.65) | PLA2G7ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL11363627 | 0.74 | PLA2G7 (0.60) | PLA2G7ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL14275399 | 0.71 | POLB (0.69) | ALDH1A1POLBMAPTCACNA1BAPBA1 | |
| SCHEMBL13431311 | 0.71 | PLA2G7 (1.00) | PLA2G7ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL8633653 | 0.70 | MMP1 (0.42) | ALDH1A1POLBMAPTCACNA1BAPBA1 | |
| SCHEMBL28360378 | 0.70 | MAPT (0.49) | PLA2G7ALDH1A1POLBMAPTCACNA1B | |
| SCHEMBL11339548 | 0.69 | ALDH1A1 (0.63) | ALDH1A1POLBMAPTTDP1LMNA | |
| SCHEMBL6116991 | 0.69 | ALDH1A1 (0.49) | PLA2G7ALDH1A1POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646678-B | heteroaryl derivatives | NIPPON SHINYAKU CO LTD | 2012-05-30 | — | — | CN | disclosed |