Ether

Ether

SCHEMBL2787072

CCOCC.O=C(O)c1ccc(C(=O)OCC2CO2)c(C(=O)O)c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.38
MGLL Q99685 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
NPC1 O15118 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1144451 0.92 DHFR (0.42) DHFRMGLL
SCHEMBL4887674 0.88 DHFR (0.43) DHFRMGLL
SCHEMBL679935 0.87 KDM4E (0.43) DHFRMGLL
SCHEMBL12177586 0.87 DHFR (0.42) DHFRMGLLNPC1KMT2APOLB
SCHEMBL2493818 0.84 DHFR (0.42) DHFRMGLLNPC1MEN1KMT2A
Ethylene Glycol SCHEMBL28442528 0.84 DHFR (0.40) DHFRMGLLNPC1KMT2APOLB
SCHEMBL21981246 0.82 CA12 (0.47) NPC1MEN1KMT2APOLB
SCHEMBL28170336 0.82 KDM4E (0.45) MGLLPOLB
Ether SCHEMBL709268 0.82 TSHR (0.54) DHFRMGLL
Ether SCHEMBL3122176 0.81 CA12 (0.46) MGLLNPC1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1572800-B2 STABILIZERS FOR HALOGENATED RESINS IN PLASTIFIED FORMULATIONS REAGENS SPA (IT) 2010-04-14 EP claimed
EP-1572800-B1 STABILIZERS FOR HALOGENATED RESINS IN PLASTIFIED FORMULATIONS REAGENS SPA (IT) 2006-09-20 EP claimed
EP-1572800-A2 STABILIZERS FOR HALOGENATED RESINS IN PLASTIFIED FORMULATIONS Reagens S.p.A. (IT) 2005-09-14 EP claimed
WO-2004037910-A9 STABILIZERS FOR HALOGENATED RESINS IN PLASTIFIED FORMULATIONS REAGENS SPA (IT) 2004-07-22 WO claimed
WO-2004037910-A2 STABILIZERS FOR HALOGENATED RESINS IN PLASTIFIED FORMULATIONS REAGENS S.P.A. (IT) 2004-05-06 WO claimed