SCHEMBL28170336

SCHEMBL28170336

C(OCC1CO1)C1CO1.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
HSD17B10 Q99714 2/20 0.42
CDC25A P30304 1/20 0.42
CDC25B P30305 1/20 0.42
POLB P06746 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
TSHR P16473 1/20 0.38
APEX1 P27695 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
CYP1A2 P05177 1/20 0.37
HPGD P15428 1/20 0.37
MGLL Q99685 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL1333606 0.85 TSHR (0.46) TDP1LMNAALDH1A1TSHRMGLL
SCHEMBL1144451 0.85 DHFR (0.42) KDM4EMGLL
SCHEMBL679935 0.85 KDM4E (0.43) KDM4EL3MBTL1LMNARAB9AMAPK1
Isophthalic Acid SCHEMBL3123384 0.83 ALDH1A1 (0.46) TDP1ALDH1A1TSHRMGLL
Phthalic Acid SCHEMBL475362 0.82 ALDH1A1 (0.50) TDP1ALDH1A1MGLL
Ether SCHEMBL2787072 0.82 DHFR (0.38) POLBMGLL
SCHEMBL4887674 0.81 DHFR (0.43) MGLL
Paraben SCHEMBL11333403 0.80 CA2 (0.53) TDP1ALDH1A1TSHRMGLL
SCHEMBL12177586 0.79 DHFR (0.42) POLBALDH1A1MAPK1TSHRMGLL
Benzoic Acid SCHEMBL283023 0.79 DAO (0.50) TDP1ALDH1A1TSHRMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108482-A The thermoplastic compounds of CBA and heat-swellable SIKA技术股份公司 2017-08-29 CN disclosed