SCHEMBL1144451

SCHEMBL1144451

O=C(O)c1ccc(C(=O)OCC2CO2)c(C(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.42
MGLL Q99685 3/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4887674 0.96 DHFR (0.43) DHFRMGLL
SCHEMBL679935 0.94 KDM4E (0.43) DHFRMGLLKDM4E
SCHEMBL12177586 0.94 DHFR (0.42) DHFRMGLL
Ether SCHEMBL2787072 0.92 DHFR (0.38) DHFRMGLL
Ethylene Glycol SCHEMBL28442528 0.91 DHFR (0.40) DHFRMGLL
SCHEMBL2493818 0.89 DHFR (0.42) DHFRMGLL
SCHEMBL155724 0.87 DHFR (0.44) DHFRMGLL
SCHEMBL28170336 0.85 KDM4E (0.45) MGLLKDM4E
SCHEMBL8766571 0.85 DHFR (0.40) DHFRMGLL
SCHEMBL31651033 0.85 DHFR (0.44) DHFRMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139170-A1 MOISTURE AND HEAT-CURABLE SEALING COMPOSITION SIKA TECHNOLOGY AG (CH) 2026-05-21 US disclosed
EP-4626995-A1 MOISTURE AND HEAT-CURABLE SEALING COMPOSITION Sika Technology AG (CH) 2025-10-08 EP disclosed
US-12325810-B2 Water-based composition with chemical cross-linking SIKA TECHNOLOGY AG (CH) 2025-06-10 US disclosed
WO-2024113146-A1 MOISTURE AND HEAT-CURABLE SEALING COMPOSITION SIKA TECHNOLOGY AG (CH) 2024-06-06 WO disclosed
EP-3818125-B1 WATER-BASED COMPOSITION WITH CHEMICAL CROSS-LINKING SIKA TECH AG (CH) 2024-05-08 EP disclosed
WO-2024043285-A1 RESIN COMPOSITION, COMPOSITE REINFORCING MATERIAL, MOLDED BODY, AND METHOD FOR RECOVERING REINFORCING FIBERS FROM COMPOSITE REINFORCING MATERIAL 旭化成株式会社 2024-02-29 WO disclosed
US-11873421-B2 Water-based composition with improved transparency SIKA TECHNOLOGY AG (CH) 2024-01-16 US disclosed
CN-115449228-B High-temperature-resistant, high-humidity-resistant and photo-aging-resistant photoelectric packaging material as well as preparation method and application thereof 汇涌进光电(浙江)有限公司 2023-11-10 CN disclosed
CN-115093732-B Low-functionality curing agent blend and high-gloss powder coating 安徽省华安进出口有限公司 2023-05-23 CN disclosed
EP-3941959-B1 WATER-BASED COMPOSITION WITH IMPROVED TRANSPARENCY SIKA TECH AG (CH) 2023-02-01 EP disclosed
US-20110030893-A1 POLYURETHANE POLYMER BASED ON AN AMPHIPHILIC BLOCK COPOLYMER AND ITS USE AS IMPACT MODIFIER SIKA TECHNOLOGY AG (CH) 2011-02-10 US disclosed
CN-101835608-A Polyamide-based laminated biaxially-stretched film, and vapor-deposited polyamide-based laminated resin film TOYO BOSEKI 2010-09-15 CN disclosed
CN-1856536-B Process for improving color of polycondensates CIBA SC HOLDING AG 2010-06-16 CN disclosed
CN-101675125-A Composition comprising an anti-bridging agent DSM IP ASSETS BV 2010-03-17 CN disclosed
CN-101395237-A Improvements in and relating to powder coating compositions crosslinked with non-cyanurate polyepoxides HEXION SPECIALTY CHEMICALS RES (US) 2009-03-25 CN disclosed
CN-101218298-A Resin composition and shaped article composed of the same TORAY INDUSTRIES (JP) 2008-07-09 CN disclosed
CN-1856536-A Process for improving color of polycondensates CIBA SC HOLDING AG (CH) 2006-11-01 CN disclosed
CN-1518585-A Hot melt adhesive composition and process for preparation of textile product DSM IP �Ʋ����޹�˾ 2004-08-04 CN disclosed
CN-1114647-C Flowable granulates TIECK S A VAN (CH) 2003-07-16 CN disclosed
CN-1310737-A Bulk particulate material TIECK S A VAN (CH) 2001-08-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139170-A1 MOISTURE AND HEAT-CURABLE SEALING COMPOSITION DDAH1, ACMSD, APEH DHFR 4101/4885MGLL 344/4885KDM4E 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.