Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 13/20 | 0.48 |
| ▸ | HTR2A | P28223 | 13/20 | 0.48 |
| ▸ | DRD3 | P35462 | 13/20 | 0.48 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699484 | 0.81 | MTNR1B (0.54) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL7697047 | 0.81 | MTNR1B (0.54) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL28140958 | 0.81 | MTNR1B (0.54) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL6682308 | 0.78 | SLC9A1 (0.52) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL19699401 | 0.78 | SLC9A1 (0.52) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL6678123 | 0.78 | SLC9A1 (0.52) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL8489071 | 0.77 | SLC9A1 (0.53) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL8489075 | 0.74 | MTNR1B (0.56) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL19706381 | 0.72 | MTNR1B (0.64) | MTNR1BSLC9A1DRD2HTR2ADRD3 | |
| SCHEMBL6680857 | 0.72 | MTNR1B (0.64) | MTNR1BSLC9A1DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102675268-A | Method for preparing (1R,2R)-2-(2,3-dihydrobenzofuran-4-yl) cyclopropanemethylamine | JINAN ZHIHE MEDICAL TECHNOLOGY CO LTD | 2012-09-19 | — | — | CN | disclosed |